Lady Gaga as Patrizia Reggiani
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The Grammy-winning singer and actress plays Maurizio Gucci's ex-wife, Patrizia Reggiani, who was convicted of hiring a hitman to murder the former head of the Gucci fashion house.
Adam Driver as Maurizio Gucci
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The Marriage Story actor stars as Maurizio Gucci, the former head of the Gucci fashion house (and Patrizia's ex-husband) who was assassinated in March 1995.
Salma Hayek as Giuseppina "Pina" Auriemma
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The Eternals actress plays Pina Auriemma, who has often been described as Patrizia Reggiani's "clairvoyant friend."
Jared Leto as Paolo Gucci
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The Morbius actor plays Paolo Gucci, the cousin of Maurizio Gucci and the grandson of Gucci founder Guccio Gucci.
Al Pacino as Aldo Gucci
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The award-winning actor plays Aldo Gucci, who was the eldest son of Gucci founder Guccio Gucci.
Jeremy Irons as Rodolfo Gucci
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The Watchmen actor plays Rodolfo Gucci, who was an Italian actor and the father of Maurizio Gucci.
Mãdãlina Ghenea as Sophia Loren
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The Romanian actress plays Sophia Loren, an Italian actress who often wore Gucci.
Reeve Carney as Tom Ford
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The Hadestown actor plays American fashion designer Tom Ford, who once served as the creative director at Gucci.
Jack Huston as Domenico De Sole
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The Fargo actor plays the current chairman of Tom Ford International, Domenico De Sole, who was previously the president and CEO of Gucci Group.
Camille Cottin as Paola Franchi
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The Killing Eve actress plays Italian interior designer Paola Franchi, who was dating Maurizio Gucci at the time of his death.